|
Symbol Name ID |
Stk11
serine/threonine kinase 11 MGI:1341870 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Gastrointestinal hemorrhage |
Intestinal bleeding |
Esophageal neoplasm |
Neoplasm of the rectum |
Rectal prolapse |
Neoplasm of the colon |
Colon cancer |
Intestinal obstruction |
Hamartomatous polyposis |
Intestinal pseudo-obstruction |
Intussusception |
Multiple gastric polyps |
Stomach cancer |
Bloody diarrhea |
Intermittent diarrhea |
Nausea and vomiting |
Vomiting |
Gastrointestinal infarctions |
Functional intestinal obstruction |
Biliary tract neoplasm |
Neoplasm of the liver |
Abnormality of the gastrointestinal tract |
Gastrointestinal carcinoma |
Neoplasm of the small intestine |
| Disease(s) Associated with STK11 | ||||||||||||||||||||||||
| pancreatic cancer | ||||||||||||||||||||||||
| Peutz-Jeghers syndrome |
| Mouse Phenotypes | cleft secondary palate |
digestive/alimentary phenotype |
abnormal exocrine pancreas morphology |
abnormal pancreatic acinus morphology |
abnormal pancreatic acinar cell morphology |
abnormal intestine morphology |
colon polyps |
duodenum polyps |
intestine polyps |
enlarged stomach |
gastric polyps |
gastrointestinal tract polyps |
increased gastrointestinal tumor incidence |
increased intestinal adenoma incidence |
abnormal digestive system physiology |
intestinal obstruction |
peritoneal inflammation |
|
| Availability | Mouse Genotype | |||||||||||||||||
| Stk11tm1.1Jish/Stk11+ | ||||||||||||||||||
| Stk11tm1.1Mlfr/Stk11+ | ||||||||||||||||||
| Stk11tm1.2Rdp/Stk11+ | ||||||||||||||||||
| Stk11tm1Mmt/Stk11+ | ||||||||||||||||||
| Stk11tm1Tpm/Stk11+ | ||||||||||||||||||
| Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Pdx1-cre)89.1Dam/0 (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Taglntm1(cre/ERT2)Feil/Tagln+ (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Sprr2f-cre)1Dcas/0 (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Isl1tm1(cre)Tmj/Isl1+ (conditional) |
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| Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(PLAT-cre)116Sdu/0 (conditional) |
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| Stk11tm1Keis/Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi/0 (conditional) |
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| Stk11tm1.1Rdp/Stk11+ Taglntm1(cre/ERT2)Feil/Tagln+ (conditional) |
* | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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